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Welcome to MGO-2017!

Cells set up sophisticated mechanisms to organize their chromosomes within the limited nuclear volume that is available in interphase. Experimental studies using genomics and microscopy approaches, at ever improving resolutions, have revealed that the 3D organization of the genome directly mirrors its biological functions, including transcriptional gene regulation, recombination, DNA replication and DNA repair. Biophysical and mathematical modelling of such experiments can provide further insights into 3D genome organization, in particular whether this organization dictates functional outputs, or the reverse, and how much variation in 3D organization is present between individual cells and tolerated over time.

During the MGO-2017 two half-days workshop, 8 internationally renown experts, with backgrounds in experimental, bioinformatics and modelling approaches of 3D genome organization, will share their expertise on recent projects where genomics and microscopy experiments are integrated using various biophysical and modelling approaches.

The workshop will take place on October 2-3, 2017 in Gif-sur-Yvette, France.

The workshop is aimed at scientists with background in (bio)physics, biology and bioinformatics, including PhD students, engineers, young and senior scientists. Participation in the workshop is free but with obligatory registration (see Registration page on this website). Registration is limited to 150 participants, on a first-come basis.

You can download here the poster of this workshop.

Invited Speakers

Kerstin Bystricky
LBME (Laboratory of Eukaryotic Molecular Biology), Toulouse

Luca Giorgetti
Friedrich Miescher Institute, Switzerland

Ivan Junier
TIMC-IMAG (Techniques for biomedical engineering and complexity management – informatics, mathematics and applications), Grenoble

Jop Kind
Hubrecht Institute, The Netherlands

Julien Mozziconacci
University Pierre and Marie Curie, Paris

Mario Nicodemi
University of Naples and National Institute for Nuclear Physics (INFN), Italy

Cédric Vaillant
Ecole Normale Supérieure, Lyon

Juan Vaquerizas
Max Planck Institute for Molecular Biomedicine, Germany

Bioinformatics Tutorial

The workshop will be followed by a half-day bioinformatics tutorial on Hi-C data analysis. During this tutorial, for a limited number of participants, 2 external experts will discuss tools for the processing of Hi-C data and the calling of functional domains (Topologically Associating Domains).

Registration is limited to 20 participants, with selection based on motivation.

Participants to the workshop who would like to attend to this tutorial should have basic knowledge of bio-informatics and should indicate their interest, including a short motivation, during the registration for the workshop (see Registration form on this website).

Tutorial instructors

Nicolas Servant
Institut Curie, Paris

Kai Kruse
Max Planck Institute for Molecular Biomedicine, Germany

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